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bio May 4, 2018

Senior Cell Biologist

BenevolentAI is a fast-growing, UK-based company focused on the application of artificial intelligence to challenge and reinvent the current process of drug discovery & development. We have a range of drug discovery programmes ranging from exploratory work through to phase II clinical studies. Our portfolio of projects covers areas including, motor neurone disease, Parkinson’s Disease, various cancers, rare diseases and many others. We are one of the top 5 biggest private AI companies in the world and have raised over $200M in funding to drive our research based out of our sites in London, Cambridge & New York. As a cell biologist within BenevolentAI, you will make important contributions across our portfolio of current projects within our laboratories based at the Babraham Research Campus, Cambridge.

At BenevolentAI, we are reimagining the way drugs are discovered through the use of AI. An important part of this is characterisation of the best drug molecules through generation of the right in vitro data to rapidly accelerate identification of molecules for clinical use. As a key part of our Biological Sciences team, you’ll make important contributions to our projects to ensure that the value of our in vitro data is maximised and increased through AI methods.

 

Job Overview & Key Responsibilities:

  • With a strong cell biology background you will work as part of a multi disciplinary team. A key aspect of your role will be to research, develop and deliver cutting edge human cell-based disease relevant models to aid target validation and project progression
  • Using your knowledge of contemporary developments in human and patient-derived models and endpoints (including multi-modal), you will be an important contributor to defining the company’s future strategy. You will use the most disease-relevant experimental systems in concert with our unique AI capability to identify the best biological targets and molecules
  • As a key contributor within a cross functional team you should be comfortable working in a fast paced, dynamic environment and on multiple projects with changing priorities and deadlines
  • You have a passion for applying scientific expertise to drug discovery collaborations. With a proactive and positive problem solving mindset you are confident to contribute strategically and implement ideas to drive targets forward
  • You will be an excellent communicator, able to collaborate with internal and external colleagues. You will be willing to share knowledge with more junior members of the team with the possibility of line management responsibilities

 

Requirements:

  • A PhD in biology, pharmacology or related field of research or equivalent experience
  • At least four years cell biology experience in an industrial or academic setting
  • Strong practical laboratory experience of contemporary cell biology as applied to recapitulating disease. Including:
      • Tissue culture, maintaining suspension and adherent cell lines
      • Experience of isolating immune cells or primary cells from tissue and optimisation of human primary cell systems including iPSCs
      • Firm understanding and application of cell biology techniques e.g. ELISA, qPCR, immuno-blot, transfections, transductions and RNAi work
      • Familiarity with the development of phenotypic assays using iPSC-based and/or primary neuronal models
      • Experience in co cultures assays, 3D culture and organoid processing
      • Experience of multi-colour flow cytometry assay development and functional cell assays
      • Experience with automated high throughput experimental design and analysis systems
      • Knowledge of confocal and high content imaging
      • Processing of human blood and disease tissue for in vitro primary cell assays
  • A strong desire to use the latest developments in cellular/organoid screening to develop new medicines
  • Experience of setting up collaborations between academic and industrial groups

 

In this role you’ll be working with scientists from our Cambridge, London and New York offices as well as an external network of collaborators so excellent communication skills are a must. You’ll also be flexible in your approach and fun to work with!

 

Benefits:

BenevolentAI is offering a highly competitive package. Benefits will include a contributory pension scheme, life cover and private medical insurance.

 

How to apply

If you would like to be considered for this role, please apply here outlining your suitability for this role, your current salary and providing your CV. 

 

The closing date for applications is 31st May 2018.